Milling in the pharmaceutical industry is a critical process, each type serving a unique purpose. Here’s a breakdown of the different types of milling and their applications.
1. Impact Milling
Impact milling uses a hammer mill. It’s ideal for brittle and dry materials.
2. Shear Milling
Shear milling involves an extruder and hand screen. It’s commonly used for deagglomeration and wet granulation.
3. Attrition Milling
Oscillating granulators are used for attrition milling. This type is primarily used for dried granulation.
4. Shear Compression Milling
Conical screening mills are used for shear compression milling. It’s suitable for both wet and dry granulation.
5. Jet Milling
Jet milling is highly effective for reducing particle size. It’s commonly used for finely ground active substances and excipients.
In addition to these specific types, various grinding mills are also used in the pharmaceutical industry:
- Laboratory Sample Mill: Designed for grinding extra hard dry materials.
- Laboratory Cutting Mill
- Laboratory Disk Mill
- Laboratory Centrifugal Mill
- Laboratory Knife Mill
- Laboratory Ball Mill
Pharmaceutical companies often micronize active pharmaceutical ingredients to improve blending and absorption. Particle reduction is also crucial for creating suspensions and solutions in pharmaceutical formulation and nanotechnology.
Milling and grinding are essential in the pharmaceutical industry, whether for manufacturing, quality control, or sample analysis. Engineers continue to research and improve the milling process.
Continue exploring, consult our experts
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