Pressing pills is a crucial process in pharmaceutical manufacturing.
It involves using a specialized machine called a tablet press.
This machine compresses powder into tablets of uniform shape and size.
The process of pressing pills involves several key steps.
4 Key Steps to Understanding Tablet Presses
1. Powder Loading
The first step is powder loading.
The powder, which contains the active pharmaceutical ingredient and other excipients, is loaded into a die cavity in the tablet press.
This powder is the raw material that will be transformed into tablets.
2. Compression
The second step is compression.
The tablet press uses two punches, an upper and a lower punch, that strike together in the die.
This action compresses the powder under high force, causing the granulated material to bond and form a hard tablet.
The compression is typically achieved through a hydraulic mechanism, where unreduced pressure is applied uniformly in all directions through static liquid.
3. Ejection
The third step is ejection.
After compression, the lower punch raises, ejecting the formed tablet out of the die.
This step ensures that the tablet is released from the machine and ready for packaging.
4. Consistency and Compliance
The use of a tablet press ensures that each tablet produced is consistent in terms of weight, size, and content uniformity.
This consistency is crucial for pharmaceutical applications.
The evolution of tablet presses has been driven by increasing demand for tablets, advancements in technology, and the need to comply with stringent regulations such as CGMP (Current Good Manufacturing Process).
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